This active female in her 40s desired improvement in her facial profile, including adding volume to the cheek area and lips, and improvement of the appearance of smile lines. Two syringes of Voluma and one syringe of Juvederm Ultra Plus were used for this purpose. We also added BOTOX to her forehead, glabella, crow’s feet, and neck to smooth out soft lines in these areas. After treatment, the patient appears natural, rejuvenated, and refreshed.